ROPIVACAINE HYDROCHLORIDE

Ropivacaine Hydrochloride

Ropivacaine hydrochloride used further in formulations which are used mainly in solution for Injection used in Parenteral application as local anaesthetics. Ropivacaine works by block the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse, and by reducing the rate of rise of the action potential. Specifically, they block the sodium-channel and decrease chances of depolarization and consequent action potentials. In general, the progression of anesthesia is related to the diameter, myelination and conduction velocity of affected nerve fibers. It blocking nerve impulses of pain transmission to the brain. The Parenteral application Indications as local dental anaesthetic peripheral nerve blocks, caudal anaesthesia, epidural spinal anaesthesia for surgery.

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CHEMISTRYCT
Name of the ProductLidocaine Base
Molecular Structure
Systematic IUPAC Name(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide;hydrochloride
CAS Number132112-35-7
PharmacopoeiaIP/BP/EP/USP
FormulaC17H29CIN2O2
Molecular Mass328.88 g/mol
PHYSICAL DATA
Physical state and appearanceSolid (Crystalline solid)
ColorWhite
OdourOdourless
Melting Point268 to 2720C
Drug TypeApproved Drug
Drug CategoryAnesthetic agent : Local aesthesia, Spinal anesthesia
Dosage FormsParenteral(sterile)
StorageIn cool temperature. Keep container tightly closed