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Ropivacaine Hydrochloride

Ropivacaine hydrochloride used further in formulations which are used mainly in solution for Injection used in Parenteral application as local anaesthetics. Ropivacaine works by block the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse, and by reducing the rate of rise of the action potential. Specifically, they block the sodium-channel and decrease chances of depolarization and consequent action potentials. In general, the progression of anesthesia is related to the diameter, myelination and conduction velocity of affected nerve fibers. It blocking nerve impulses of pain transmission to the brain. The Parenteral application Indications as local dental anaesthetic peripheral nerve blocks, caudal anaesthesia, epidural spinal anaesthesia for surgery.

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Name of the Product Lidocaine Base
Molecular Structure
Systematic IUPAC Name (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide;hydrochloride
CAS Number 132112-35-7
Pharmacopoeia IP/BP/EP/USP
Formula C17H29CIN2O2
Molecular Mass 328.88 g/mol
Physical state and appearance Solid (Crystalline solid)
Color White
Odour Odourless
Melting Point 268 to 2720C
Drug Type Approved Drug
Drug Category Anesthetic agent : Local aesthesia, Spinal anesthesia
Dosage Forms Parenteral(sterile)
Storage In cool temperature. Keep container tightly closed