Lidocaine Base

Lidocaine

Lidocaine Base used further in formulations which are used mainly in topical application to relieve itching, burning and pain of inflamed skin. It inhibit ion fluxes across membranes, particularly sodium transport across the cell membrane decreases increasing depolarization phase action potential blocking nerve action potential.

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CHEMISTRY
Name of the Product Lidocaine Base
Molecular Structure
Systematic IUPAC Name 2-(diethylamino)-N-(2,6-dimethylphenyl) acetamide
CAS Number 137-58-6
Pharmacopoeia USP/BP/EP
Formula C14H22N2O
Molecular Mass 234.34 g/mol
PHYSICAL DATA
Physical state and appearance Solid (Crystalline solid)
Color White
Odour Characteristic
Melting Point 66oC to 70oC
Drug Type Approved Drug
Therapeutic Category Antiarrhythmic Agents, Anesthetics
Dosage Forms Cream, Gel, Implant, Jelly, Kit6. Liquid, Ointment, Solution, Spray
Storage Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 400C (1040F).
(preferably store at temperature between 150C and 300C)