Bupivacaine hydrochloride used further in formulations which are used mainly in Parenteral application as long acting local anaesthetics. It works by blocking the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse, and by reducing the rate of rise of the action potential. In general, the progression of anaesthesia is related to the diameter, myelination, and conduction velocity of affected nerve fibres. The Parenteral application Indications as local dental anaesthetic peripheral nerve blocks, caudal anaesthesia, epidural spinal anaesthesia for surgery.
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|Name of the Product||Lidocaine Base|
|Systematic IUPAC Name||2-(diethylamino)-N-(2,6-dimethylphenyl) acetamide|
|Molecular Mass||288.8 g/mol|
|Physical state and appearance||Solid (Crystalline solid)|
|Melting Point||1070 to 1080C|
|Drug Type||Approved Drug|
|Drug Category||Anesthetic agent : Local aesthesia, Spinal anesthesia|
|Dosage Forms||Gel, Parenteral (sterile).|
|Storage||Store at controlled room temperature of 15-30°C (59-86°F). Protect from freezing and extreme heat.|