Lidocaine Base

Lidocaine Base used further in formulations which are used mainly in topical application to relieve itching, burning and pain of inflamed skin. It inhibit ion fluxes across membranes, particularly sodium transport across the cell membrane decreases increasing depolarization phase action potential blocking nerve action potential.

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CHEMISTRY

Name of the Product	Lidocaine Base
Molecular Structure
Systematic IUPAC Name	2-(diethylamino)-N-(2,6-dimethylphenyl) acetamide
CAS Number	137-58-6
Pharmacopoeia	USP/BP/EP
Formula	C₁₄H₂₂N₂O
Molecular Mass	234.34 g/mol

PHYSICAL DATA

Physical state and appearance	Solid (Crystalline solid)
Color	White
Odour	Characteristic
Melting Point	66^oC to 70^oC
Drug Type	Approved Drug
Therapeutic Category	Antiarrhythmic Agents, Anesthetics
Dosage Forms	Cream, Gel, Implant, Jelly, Kit6. Liquid, Ointment, Solution, Spray
Storage	Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 40⁰C (104⁰F). (preferably store at temperature between 15⁰C and 30⁰C)

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